GM23716
                                                
                                                iPSC from Fibroblast
                                                
                                                
                                             
                                            
                                                
                                                    
                                                         Description:
                                                    
                                                    
                                                         
                                                            
                                                            APPARENTLY HEALTHY FETAL TISSUE 
                                                            
                                                    
                                                 
                                                
                                                
                                                
                                                
                                             
                                         
                                     
                                    
                                        
                                            
                                            
                                            
                                            
                                                
                                                    
                                                        
                                                            
                                                            
                                                                
                                                                    
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                                                                            Repository
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                                                                            NIGMS Human Genetic Cell Repository
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	| Subcollection | 
	Apparently healthy iPSCs Apparently Healthy Collection | 
 
                                                                
                                                                
                                                                
                                                                
                                                                
                                                                
	| Protocols | 
	Protocol PDF | 
 
                                                                
                                                                    
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                                                                            Biopsy Source
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                                                                            Skin
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                                                                            Cell Type
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                                                                            Stem cell
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                                                                            Cell Subtype
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                                                                            Induced pluripotent stem cell
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                                                                            Transformant
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                                                                            Reprogrammed (Episomal)
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                                                                            Sample Source
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                                                                            iPSC from Fibroblast
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                                                                            Race
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                                                                            Black/African American
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                                                                            Family Member
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                                                                            1
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                                                                            Relation to Proband
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                                                                            proband
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                                                                            Confirmation
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                                                                            Karyotypic analysis and Case history
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                                                                            ISCN
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                                                                            46,XX[19]
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                                                                            Species
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                                                                            Homo sapiens
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                                                                            Common Name
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                                                                            Human
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                                                                            Remarks
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	| Induced Pluripotent Stem Cell | 
	The frozen cell line submitted to the Repository  was recovered and expanded. The expanded line was evaluated for viability  surface antigen expression and alkaline phosphatase activity. Pluripotency was assessed via embryoid body (EB) formation and PluriTest. Steady-state mRNA expression patterns of undifferentiated iPSC and EBs were determined via real-time PCR. Characterization data are included in the Certificate of Analysis. | 
 
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	| Remarks | 
	Induced pluripotent stem cell line derived from  GM06111 Fibroblast. Researchers purchasing hiPSCs from the NIGMS Repository are responsible for any limited use label licenses (LULLs) applicable to the cell line purchased. The applicable  LULL to this line is WARF. | 
 
                                                                
                                                             
                                                            
                                                            
                                                         
                                                     
                                                 
                                                
                                                    
                                                        
                                                            
                                                            
                                                            
                                                                
	| Lee YJ, Cho B, Kwon D, Kim Y, An S, Kang S, Kim J, Catalpol promotes the generation of cerebral organoids with oRGs through activation of STAT3 signaling Bioengineering & translational medicine10:e10746 2024 | 
 
	| PubMed ID: 40385540 | 
 
                                                                
                                                             
                                                            
                                                         
                                                     
                                                 
                                                
                                                
                                                
                                             
                                         
                                     
                                 
                                
                             
                         
                     
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